Ccdc136 Gene Summary [Mouse]
Involved in acrosome assembly and single fertilization. Located in acrosomal membrane. Is expressed in cerebral cortex and retina. Orthologous to human CCDC136 (coiled-coil domain containing 136). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Ccdc136 |
| Official Name | coiled-coil domain containing 136 [Source:MGI Symbol;Acc:MGI:1918128] |
| Ensembl ID | ENSMUSG00000029769 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 136 |
| Synonyms | 4921511K06Rik, coiled-coil domain containing 136, DKFZp434G156, NAG6, RGD1564459 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ccdc136 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- RecF/RecN/SMC N terminal domain
- chromosome segregation protein SMC, common bacterial type
- chromosome segregation protein SMC, primarily archaeal type
- Ciliary protein causing Leber congenital amaurosis disease
- Synaptonemal complex protein 1 (SCP-1)
- Intermediate filament protein
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ccdc136 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- acrosome assembly
- spermatogenesis
- single fertilization
Cellular Component
Where in the cell the gene product is active
- acrosomal membrane