Sult2a8 Gene Summary [Mouse]
Enables 3'-phosphoadenosine 5'-phosphosulfate binding activity and sulfotransferase activity. Involved in bile acid catabolic process. Located in cytosol. Is expressed in liver and olfactory epithelium. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human SULT2A1 (sulfotransferase family 2A member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Sult2a8 |
| Official Name | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8 [Source:MGI Symbol;Acc:MGI:1924221] |
| Ensembl ID | ENSMUSG00000030378 |
| Bio databases IDs | |
| Aliases | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8 |
| Synonyms | 2810007J24Rik, L-STL, mL-STL, sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8, sulphotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8, Sult1 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sult2a8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- bile-salt sulfotransferase
- sulfotransferase
- steroid sulfotransferase
- Sulfotransferase domain
- alcohol sulfotransferase
- enzyme
- 3'-phosphoadenosine 5'-phosphosulfate binding
Pathways
Biological processes and signaling networks where the Sult2a8 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol