Disp1 Gene Summary [Mouse]
Enables molecular carrier activity. Acts upstream of or within several processes, including embryonic pattern specification; patched ligand maturation; and regionalization. Predicted to be active in membrane. Is expressed in several structures, including embryo ectoderm; foot bone; notochord; palatal shelf; and urinary system. Orthologous to human DISP1 (dispatched RND transporter family member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Disp1 |
| Official Name | dispatched RND transporter family member 1 [Source:MGI Symbol;Acc:MGI:1916147] |
| Ensembl ID | ENSMUSG00000030768 |
| Bio databases IDs | |
| Aliases | dispatched RND transporter family member 1 |
| Synonyms | 1190008H24Rik, DISPA, dispatched RND transporter family member 1, RP11 452F193 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Disp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Patched family
- transmembrane domain
- Sterol-sensing domain of SREBP cleavage-activation
- protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Disp1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- embryonic pattern specification
- smoothened signaling pathway
- diaphragm development
- peptide transport
- determination of left/right symmetry
- patched ligand maturation
- dorsal/ventral pattern formation
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- protein binding