Rnf133 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Involved in protein autoubiquitination. Located in endoplasmic reticulum membrane. Is expressed in several structures, including brain; male reproductive gland or organ; respiratory system; submandibular gland; and thymus. Orthologous to human RNF133 (ring finger protein 133). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnf133 |
| Official Name | ring finger protein 133 [Source:MGI Symbol;Acc:MGI:2677436] |
| Ensembl ID | ENSMUSG00000051956 |
| Bio databases IDs | |
| Aliases | ring finger protein 133 |
| Synonyms | Greul2, LOC681784, ring finger protein 133 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf133 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PA domain
- PA
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- Ring finger domain
- RING-like zinc finger
- RING-H2 zinc finger domain
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rnf133 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein autoubiquitination
- ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- cytoplasm
- late endosome
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- metal ion binding