Pgk2 Gene Summary [Mouse]
Enables phosphoglycerate kinase activity. Acts upstream of or within flagellated sperm motility and glycolytic process. Located in sperm fibrous sheath. Is expressed in germ cell of testis and testis. Orthologous to human PGK2 (phosphoglycerate kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pgk2 |
| Official Name | phosphoglycerate kinase 2 [Source:MGI Symbol;Acc:MGI:97563] |
| Ensembl ID | ENSMUSG00000031233 |
| Bio databases IDs | |
| Aliases | phosphoglycerate kinase 2 |
| Synonyms | phosphoglycerate kinase 2, Tcp-2 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pgk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Phosphoglycerate_kinase
- phosphoglycerate kinase
- ATP binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- sperm fibrous sheath
- cytoplasmic droplets