Nlrp2

Predicted to enable several functions, including Pyrin domain binding activity; aspartic-type endopeptidase inhibitor activity; and caspase binding activity. Predicted to be involved in regulation of inflammatory response. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in cytoplasm. Predicted to colocalize with chromosome, telomeric region. Is expressed in early conceptus and gonad. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to several human genes including NLRP2 (NLR family pyrin domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nlrp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Nlrp2 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.