Slc45a1 Gene Summary [Mouse]

Enables D-glucose:proton symporter activity. Involved in D-glucose transmembrane transport. Predicted to be active in membrane. Is expressed in medulla oblongata basal plate and ventral grey horn. Orthologous to human SLC45A1 (solute carrier family 45 member 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc45a1
Official Name
solute carrier family 45, member 1 [Source:MGI Symbol;Acc:MGI:2653235]
Ensembl ID
ENSMUSG00000039838
Bio databases IDs NCBI: 242773 Ensembl: ENSMUSG00000039838
Aliases solute carrier family 45, member 1
Synonyms C230078B22, DNB5, IDDNPF, PAST-A, solute carrier family 45 member 1, solute carrier family 45, member 1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Slc45a1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • hexose transporter
  • Major Facilitator Superfamily
  • galactose:hydrogen symporter
  • hydrogen:glucose transporter
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • D-glucose
  • galactose
regulated by
  • beta-estradiol
  • ACSS2
  • MirBART2
  • acetate
disease
  • schizophrenia
  • intellectual developmental disorder with neuropsychiatric features
  • breast carcinoma

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Slc45a1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sucrose transport
  • galactose transport

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • sucrose:hydrogen symporter activity
  • galactose:hydrogen symporter activity
  • hydrogen:glucose symporter activity

Gene-Specific Assays for Results You Can Trust

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