Cluh Gene Summary [Mouse]
Predicted to enable mRNA binding activity. Predicted to be involved in intracellular distribution of mitochondria and mitochondrion organization. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; genitourinary system; gut; musculature; and naris. Orthologous to human CLUH (clustered mitochondria homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cluh |
| Official Name | clustered mitochondria (cluA/CLU1) homolog [Source:MGI Symbol;Acc:MGI:1921398] |
| Ensembl ID | ENSMUSG00000020741 |
| Bio databases IDs | |
| Aliases | clustered mitochondria (cluA/CLU1) homolog |
| Synonyms | 1300001I01Rik, CLU1, clustered mitochondria homolog, KIAA0664, LOC105371591, mKIAA0664, RGD1307222 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cluh often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Clustered mitochondria
- mRNA binding
- Mitochondrial function, CLU-N-term
- protein binding
- tetratricopeptide repeat
- An uncharacterized central domain of CLU mitochondrial proteins
- translation regulator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- uterine leiomyoma
- leiomyomatosis
- Alzheimer disease
role in cell
- mitophagy in
- elongation
- organization
- elongation in
- replication in
- induction in
- distribution in
- distribution
- clustering
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribonucleoprotein granule
- Golgi Apparatus
- Endoplasmic Reticulum
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cluh gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- intracellular distribution of mitochondria
- mitochondrion organization
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- mRNA binding