Ranbp17 Gene Summary [Mouse]

Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to act upstream of or within nucleocytoplasmic transport. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. Orthologous to human RANBP17 (RAN binding protein 17). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Ranbp17
Official Name
RAN binding protein 17 [Source:MGI Symbol;Acc:MGI:1929706]
Ensembl ID
ENSMUSG00000040594
Bio databases IDs NCBI: 66011 Ensembl: ENSMUSG00000040594
Aliases RAN binding protein 17
Synonyms RAN binding protein 17, RGD1562576
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ranbp17 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme binding
  • Importin-beta N-terminal domain
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • metabolic syndrome X
  • essential tremor
  • ischemic stroke
  • restless legs syndrome
  • migraines
  • nicotine dependence
  • infection by HIV-1
role in cell
  • growth
  • reverse transcription in
  • reverse transcription

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ranbp17 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein import into nucleus
  • protein export from nucleus
  • mRNA transport

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nuclear pore

Molecular Function

What the gene product does at the molecular level
  • GTP binding
  • small GTPase binding
  • nuclear export signal receptor activity

Gene-Specific Assays for Results You Can Trust

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