Xpo7 Gene Summary [Mouse]
Predicted to enable nuclear export signal receptor activity. Predicted to be involved in protein export from nucleus. Predicted to act upstream of or within nucleocytoplasmic transport. Predicted to be located in nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. Is expressed in heart and liver. Orthologous to human XPO7 (exportin 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Xpo7 |
| Official Name | exportin 7 [Source:MGI Symbol;Acc:MGI:1929705] |
| Ensembl ID | ENSMUSG00000022100 |
| Bio databases IDs | |
| Aliases | exportin 7 |
| Synonyms | 4930506C02RIK, EXP7, exportin 7, RANBP16 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Xpo7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme binding
- protein binding
- Importin-beta N-terminal domain
- nuclear export signal receptor
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- anemia
- Alzheimer disease
- cancer
- liver neoplasia
- epithelial neoplasia
- epithelial cancer
- liver cancer
- organismal death
- atrial fibrillation
- digestive system cancer
role in cell
- expression in
- senescence
- quantity
- condensation in
- density
- size
- oncogene-induced senescence
- replicative senescence
- condensation
- enucleation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- nuclear pores
- nuclear envelope
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Xpo7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein export from nucleus
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- protein binding
- small GTPase binding
- nuclear export signal receptor activity