Oasl1 Gene Summary [Mouse]
Enables double-stranded RNA binding activity. Involved in interleukin-27-mediated signaling pathway. Predicted to be located in cytoplasm and nucleolus. Predicted to be active in cytosol; membrane; and nucleoplasm. Is expressed in testis. Orthologous to human OASL (2'-5'-oligoadenylate synthetase like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Oasl1 |
| Official Name | 2'-5' oligoadenylate synthetase-like 1 [Source:MGI Symbol;Acc:MGI:2180849] |
| Ensembl ID | ENSMUSG00000041827 |
| Bio databases IDs | |
| Aliases | 2'-5' oligoadenylate synthetase-like 1 |
| Synonyms | 2'-5' oligoadenylate synthetase-like 1, 7530414C13Rik, oasl9 |
| Species | Mouse, Mus musculus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Oasl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ubiquitin family
- 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
- Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
- Ubl1_cv_Nsp3_N-like
- double-stranded RNA binding
- Ubiquitin homologues
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
- nucleoplasm
- nucleoli