Sprr2i Gene Summary [Mouse]

Predicted to enable lipid binding activity. Predicted to be a structural constituent of skin epidermis. Predicted to be involved in keratinocyte differentiation. Predicted to be located in cornified envelope and cytoplasm. Predicted to be active in extracellular region and secretory granule. Orthologous to several human genes including SPRR2A (small proline rich protein 2A); SPRR2B (small proline rich protein 2B); and SPRR2D (small proline rich protein 2D). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sprr2i
Official Name
small proline-rich protein 2I [Source:MGI Symbol;Acc:MGI:1330309]
Ensembl ID
ENSMUSG00000042157
Bio databases IDs NCBI: 20763 Ensembl: ENSMUSG00000042157
Aliases small proline-rich protein 2I
Synonyms small proline-rich protein 2I
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sprr2i often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • lipid binding
  • structural constituent of epidermis

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cornified envelope
  • Extracellular Space
  • secretory granules

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.