Fscb Gene Summary [Mouse]

Enables calcium ion binding activity. Involved in negative regulation of protein sumoylation. Located in sperm fibrous sheath and sperm principal piece. Is expressed in male reproductive gland or organ. Orthologous to human FSCB (fibrous sheath CABYR binding protein). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Fscb
Official Name
fibrous sheath CABYR binding protein [Source:MGI Symbol;Acc:MGI:3646964]
Ensembl ID
ENSMUSG00000043060
Bio databases IDs NCBI: 623046 Ensembl: ENSMUSG00000043060
Aliases fibrous sheath CABYR binding protein
Synonyms C14orf155, EG623046, fibrous sheath CABYR binding protein
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fscb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • calcium ion binding
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • membrane surface
  • sperm fibrous sheath

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Fscb gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • negative regulation of protein sumoylation

Cellular Component

Where in the cell the gene product is active
  • sperm principal piece
  • flagellar fibrous sheath

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.