Cabyr Gene Summary [Mouse]
Enables calcium ion binding activity and protein domain specific binding activity. Predicted to be involved in calcium-mediated signaling and sperm capacitation. Located in cytoplasm and sperm flagellum. Used to study male infertility. Orthologous to human CABYR (calcium binding tyrosine phosphorylation regulated). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cabyr |
| Official Name | calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) [Source:MGI Symbol;Acc:MGI:1918382] |
| Ensembl ID | ENSMUSG00000024430 |
| Bio databases IDs | |
| Aliases | calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2) |
| Synonyms | 1700016C01Rik, 4933421A18Rik, CABYRa, CABYRc, CABYRc/d, CABYRe, calcium binding tyrosine phosphorylation regulated, CBP86, CT88, FSP-2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cabyr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calcium ion binding
- enzyme binding
- protein domain specific binding
- protein binding
- DD_R_PKA_DPY30-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- motile cilia
- sperm end piece
- flagella
- cytosol
- nucleoplasm
- sperm tail
- sperm fibrous sheath
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cabyr gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm capacitation
- epithelial cilium movement
Cellular Component
Where in the cell the gene product is active
- nucleus
- motile cilium
- cytoskeleton
- cytoplasm
- cytosol
- sperm principal piece
- flagellar fibrous sheath
- extracellular region
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- calcium ion binding
- SH3 domain binding