Adamtsl5 Gene Summary [Mouse]
Predicted to enable heparin binding activity and microfibril binding activity. Located in extracellular matrix. Is expressed in several structures, including alimentary system; liver and biliary system; mesothelium; musculoskeletal system; and sensory organ. Orthologous to human ADAMTSL5 (ADAMTS like 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Adamtsl5 |
| Official Name | ADAMTS-like 5 [Source:MGI Symbol;Acc:MGI:1913798] |
| Ensembl ID | ENSMUSG00000043822 |
| Bio databases IDs | |
| Aliases | ADAMTS-like 5 |
| Synonyms | 2010109H09Rik, ADAMTS-like 5, LOC100503741, THSD6 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adamtsl5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Thrombospondin type 1 repeats
- NTR_like
- Thrombospondin type 1 domain
- ADAM-TS Spacer 1
- ADAMTS cysteine-rich domain
- protein binding
- Spondin-like TSP1 domain
- heparin binding
- microfibril binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- microfibrils
- extracellular matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adamtsl5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- extracellular matrix organization
Cellular Component
Where in the cell the gene product is active
- microfibril
- extracellular matrix
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- heparin binding
- microfibril binding