Rgs4

Predicted to enable G-protein alpha-subunit binding activity; GTPase activator activity; and protein kinase binding activity. Predicted to be involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; negative regulation of transmembrane transport; and regulation of signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human RGS4 (regulator of G protein signaling 4). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rgs4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Rgs4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rgs4 gene, providing context for its role in the cell.