Npb Gene Summary [Mouse]
Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and feeding behavior. Predicted to act upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway. Predicted to be located in extracellular space. Orthologous to human NPB (neuropeptide B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Npb |
| Official Name | neuropeptide B [Source:MGI Symbol;Acc:MGI:2387153] |
| Ensembl ID | ENSMUSG00000044034 |
| Bio databases IDs | |
| Aliases | neuropeptide B |
| Synonyms | LOC653419, mPPL7, neuropeptide B, PPL7, PPNPB |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Npb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Neuropeptides B and W
- G-protein-coupled receptor binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Npb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- G-protein coupled receptor signaling pathway
- feeding behavior
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- G-protein coupled receptor binding
- protein binding