Dph7 Gene Summary [Mouse]
Predicted to enable diphthine methylesterase activity and protein methylesterase activity. Predicted to be involved in protein histidyl modification to diphthamide. Predicted to be active in cytoplasm. Orthologous to human DPH7 (diphthamide biosynthesis 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dph7 |
| Official Name | diphthamine biosynethesis 7 [Source:MGI Symbol;Acc:MGI:1914478] |
| Ensembl ID | ENSMUSG00000026975 |
| Bio databases IDs | |
| Aliases | diphthamine biosynethesis 7 |
| Synonyms | 2810443J12Rik, C9orf112, diphthamide biosynthesis 7, diphthamine biosynethesis 7, LOC102724259, RGD1304868, RRT2, WDR85 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dph7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- carboxylic ester hydrolase
- WD40 repeats
- WD domain, G-beta repeat
- enzyme
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dph7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-diphthamide biosynthetic process from peptidyl-histidine
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding