Catsperb Gene Summary [Mouse]

Predicted to act upstream of or within sperm capacitation. Located in sperm principal piece. Part of CatSper complex. Is expressed in germ cell of testis; seminiferous tubule; spermatid; spermatocyte; and testis. Orthologous to human CATSPERB (cation channel sperm associated auxiliary subunit beta). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Processed Transcript
Official Symbol
Catsperb
Official Name
cation channel sperm associated auxiliary subunit beta [Source:MGI Symbol;Acc:MGI:2443988]
Ensembl ID
ENSMUSG00000047014
Bio databases IDs NCBI: 271036 Ensembl: ENSMUSG00000047014
Aliases cation channel sperm associated auxiliary subunit beta
Synonyms 4931410B03, 4932415G16Rik, C14orf161, cation channel sperm associated auxiliary subunit beta, cation channel sperm associated auxiliary subunit β, Catsper beta, CatSper(beta), Catsper β, CatSper(β), LOC100911278, LOC102553227
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Catsperb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Cation channel sperm-associated protein subunit beta protein family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • male infertility
  • venous thromboembolism
  • Alzheimer disease
  • open-angle glaucoma
regulated by
role in cell
  • capacitation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cilia

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Catsperb gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • spermatogenesis
  • cell differentiation

Cellular Component

Where in the cell the gene product is active
  • cilium
  • sperm principal piece
  • plasma membrane
  • CatSper complex