Gpr157

Enables G protein-coupled receptor activity. Involved in circadian behavior; phospholipase C-activating G protein-coupled receptor signaling pathway; and radial glial cell differentiation. Located in ciliary membrane. Is expressed in cerebral cortex ventricular layer; neocortex; and telencephalon ventricular layer. Orthologous to human GPR157 (G protein-coupled receptor 157). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gpr157 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gpr157 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Gpr157 gene, providing context for its role in the cell.