Isg20l2 Gene Summary [Mouse]
Predicted to enable exonuclease activity. Predicted to be involved in RNA processing. Predicted to be located in nucleolus. Predicted to be active in nucleus. Is expressed in several structures, including brain ventricular layer; dorsal root ganglion; submandibular gland primordium; thymus primordium; and tooth. Orthologous to human ISG20L2 (interferon stimulated exonuclease gene 20 like 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Isg20l2 |
| Official Name | interferon stimulated exonuclease gene 20-like 2 [Source:MGI Symbol;Acc:MGI:2140076] |
| Ensembl ID | ENSMUSG00000048039 |
| Bio databases IDs | |
| Aliases | interferon stimulated exonuclease gene 20-like 2 |
| Synonyms | 4930429N24, exon, FLJ12671, HSD38, interferon stimulated exonuclease gene 20-like 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Isg20l2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily
- exonuclease
- EXOIII
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Isg20l2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ribosome biogenesis
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
Molecular Function
What the gene product does at the molecular level
- 3'-5'-exoribonuclease activity
- RNA binding
- protein binding
- exonuclease activity