Zc3h18 Gene Summary [Mouse]

Predicted to enable mRNA cap binding complex binding activity and protein-macromolecule adaptor activity. Predicted to be involved in RNA destabilization. Predicted to be located in nuclear speck. Predicted to be part of ribonucleoprotein complex. Is expressed in respiratory system cartilage; sensory organ; skeleton; and vibrissa. Orthologous to human ZC3H18 (zinc finger CCCH-type containing 18). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zc3h18
Official Name
zinc finger CCCH-type containing 18 [Source:MGI Symbol;Acc:MGI:1923264]
Ensembl ID
ENSMUSG00000017478
Bio databases IDs NCBI: 76014 Ensembl: ENSMUSG00000017478
Aliases zinc finger CCCH-type containing 18
Synonyms 1190001B23Rik, 5830416A07Rik, NHN1, zinc finger CCCH-type containing 18
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zc3h18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • zinc finger
  • RNA-binding, Nab2-type zinc finger
  • binding protein
  • CCCH-type zinc finger
  • protein binding activity, bridging
  • Zinc finger C-x8-C-x5-C-x3-H type (and similar)
  • protein binding
  • zinc finger domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Wilms tumor
  • Wilms tumorigenesis
regulated by
regulates
  • NFkB (complex)
  • CD274
  • IKK (complex)
role in cell
  • expression in
  • activation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Zc3h18 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA destabilization

Cellular Component

Where in the cell the gene product is active
  • nuclear speck
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • metal ion binding
  • protein binding, bridging

Gene-Specific Assays for Results You Can Trust

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