Defb19 Gene Summary [Mouse]
Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in antifungal innate immune response; defense response to Gram-negative bacterium; and defense response to Gram-positive bacterium. Predicted to be located in extracellular region. Is expressed in metanephros and reproductive system. Used to study female reproductive system disease. Orthologous to human DEFB119 (defensin beta 119). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Defb19 |
| Official Name | defensin beta 19 [Source:MGI Symbol;Acc:MGI:2385955] |
| Ensembl ID | ENSMUSG00000050645 |
| Bio databases IDs | |
| Aliases | defensin beta 19 |
| Synonyms | BD-19, Beta-defensin 19, DEFB120, DEFB-19, DEFB-20, Defb24, defensin beta 119, defensin beta 19, defensin beta 24, defensin β 119, defensin β 19, defensin β 24, ESC42-RELA, ESC42-RELB, mBD-19, Tdl, β-defensin 19 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Defb19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Beta defensin
- lipopolysaccharide binding
Pathways
Biological processes and signaling networks where the Defb19 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Defb19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to Gram-negative bacterium
- defense response to Gram-positive bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular region
Molecular Function
What the gene product does at the molecular level
- lipopolysaccharide binding