Serpinb1b Gene Summary [Mouse]
Contributes to serine-type endopeptidase inhibitor activity. Involved in negative regulation of interleukin-1 beta production. Acts upstream of or within regulation of protein catabolic process. Predicted to be located in cytoplasmic ribonucleoprotein granule and extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; brain; dorsal grey horn; naris; and physiological umbilical hernia dermis. Orthologous to human SERPINB1 (serpin family B member 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Serpinb1b |
| Official Name | serine (or cysteine) peptidase inhibitor, clade B, member 1b [Source:MGI Symbol;Acc:MGI:2445361] |
| Ensembl ID | ENSMUSG00000051029 |
| Bio databases IDs | |
| Aliases | serine (or cysteine) peptidase inhibitor, clade B, member 1b |
| Synonyms | 6330533H24Rik, EIB, LOC102553010, ovalbumin, RGD1560658, serine (or cysteine) peptidase inhibitor, clade B, member 1b, Serpin1b1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Serpinb1b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SERine Proteinase INhibitors (serpin) family
- protease inhibitor
- serine protease inhibitor activity
- enzyme
- protein binding
- Serpin (serine protease inhibitor)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- cytoplasmic ribonucleoprotein granule