Mtln Gene Summary [Mouse]
Involved in several processes, including positive regulation of fatty acid beta-oxidation; positive regulation of sequestering of calcium ion; and striated muscle cell differentiation. Located in mitochondrial inner membrane. Is expressed in Meckel's cartilage; axial skeleton; esophagus; heart; and retina nuclear layer. Orthologous to human MTLN (mitoregulin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mtln |
| Official Name | mitoregulin [Source:MGI Symbol;Acc:MGI:1915135] |
| Ensembl ID | ENSMUSG00000051319 |
| Bio databases IDs | |
| Aliases | mitoregulin |
| Synonyms | 1500011K16Rik, LEMP, LINC00116, mitoregulin, MOXI, MPM, Mtln peptide, NCRNA00116, SMIM37 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mtln often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- clopidogrel
role in cell
- expression in
- apoptosis
- binding in
- differentiation
- glycolysis in
- accumulation in
- oxidation in
- transactivation in
- respiration
- lipolysis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mtln gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of mitochondrial membrane potential
- fatty acid beta-oxidation
- striated muscle cell differentiation
- positive regulation of fatty acid beta-oxidation
- positive regulation of sequestering of calcium ion
- cellular lipid metabolic process
- cellular respiration
- triglyceride homeostasis
- positive regulation of protein complex assembly
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding