Adgrg4 Gene Summary [Mouse]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human ADGRG4 (adhesion G protein-coupled receptor G4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Adgrg4
Official Name
adhesion G protein-coupled receptor G4 [Source:MGI Symbol;Acc:MGI:2685213]
Ensembl ID
ENSMUSG00000053852
Bio databases IDs NCBI: 236798 Ensembl: ENSMUSG00000053852
Aliases adhesion G protein-coupled receptor G4
Synonyms adhesion G protein-coupled receptor G4, EG666362, Gm367, GPR112, Gpr112l, PGR17, RGD1564057, RP1-299I16
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adgrg4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • 7 transmembrane receptor (Secretin family)
  • Family of unknown function (DUF5585)
  • LamG
  • GPCR proteolysis site, GPS, motif
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Adgrg4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • cancer
  • Alzheimer disease

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Adgrg4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway
  • cell surface receptor signaling pathway
  • adenylate cyclase-activating G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.