Tyw1 Gene Summary [Mouse]

Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and tRNA-4-demethylwyosine synthase activity. Predicted to be involved in wybutosine biosynthetic process. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to several human genes including TYW1 (tRNA-yW synthesizing protein 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Tyw1
Official Name
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2141161]
Ensembl ID
ENSMUSG00000056310
Bio databases IDs NCBI: 100929 Ensembl: ENSMUSG00000056310
Aliases tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms Rsafd1, tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Species
Mouse, Mus musculus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tyw1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Radical_SAM
  • Radical SAM superfamily
  • flavodoxin
  • wyosine biosynthesis protein TYW1
  • Wyosine base formation
  • NADPH-dependent FMN reductase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
phenotypes
  • decreased vertical activity
  • impaired pupillary reflex

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.