Trank1 Gene Summary [Mouse]
Is expressed in adrenal cortex; central nervous system; frenulum; lung; and seminiferous cord. Orthologous to human TRANK1 (tetratricopeptide repeat and ankyrin repeat containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trank1 |
| Official Name | tetratricopeptide repeat and ankyrin repeat containing 1 [Source:MGI Symbol;Acc:MGI:1341834] |
| Ensembl ID | ENSMUSG00000062296 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat and ankyrin repeat containing 1 |
| Synonyms | A230061D21RIK, C030048J01RIK, Gm187, KIAA0342, LBA1, RGD1563130, tetratricopeptide repeat and ankyrin repeat containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trank1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- Ankyrin repeats (3 copies)
- Region in Clathrin and VPS
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- schizophrenia
- Alzheimer disease
- ulcerative colitis
- metabolic syndrome X
- pervasive developmental disorder
- bipolar disorder
- non-insulin-dependent diabetes mellitus
- early missed abortion
- hypothyroidism
- hemimegalencephaly
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus