Pstk Gene Summary [Mouse]

Enables L-seryl-tRNA(Sec) kinase activity and tRNA binding activity. Acts upstream of or within selenocysteine incorporation. Located in mitochondrion. Orthologous to human PSTK (phosphoseryl-tRNA kinase). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pstk
Official Name
phosphoseryl-tRNA kinase [Source:MGI Symbol;Acc:MGI:2685945]
Ensembl ID
ENSMUSG00000063179
Bio databases IDs NCBI: 214580 Ensembl: ENSMUSG00000063179
Aliases phosphoseryl-tRNA kinase
Synonyms 5430423O14RIK, 5730458D16Rik, C10orf89, Gm1099, phosphoseryl-tRNA kinase, RGD1564300
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pstk often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • tRNA binding
  • Chromatin associated protein KTI12
  • NK
  • alcohol group acceptor phosphotransferase
  • enzyme
  • O-phosphoseryl-tRNASec kinase
  • AAA domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • migraines
regulated by
  • tetrachlorodibenzodioxin
  • E. coli B5 lipopolysaccharide
regulates
role in cell
  • cohesion in
  • cohesion

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pstk gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • translation

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • L-seryl-tRNA(Sec) kinase activity
  • tRNA binding
  • kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.