PSTK Gene Summary [Human]
Predicted to enable kinase activity and tRNA binding activity. Predicted to be involved in phosphorylation; selenocysteinyl-tRNA(Sec) biosynthetic process; and translation. Predicted to act upstream of or within selenocysteine incorporation. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | PSTK |
| Official Name | phosphoseryl-tRNA kinase [Source:HGNC Symbol;Acc:HGNC:28578] |
| Ensembl ID | ENSG00000179988 |
| Bio databases IDs | |
| Aliases | phosphoseryl-tRNA kinase, L-seryl-tRNA(Sec) kinase, O-phosphoseryl-tRNA(Sec) kinase |
| Synonyms | 5430423O14RIK, 5730458D16Rik, C10orf89, Gm1099, phosphoseryl-tRNA kinase, RGD1564300 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PSTK often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- tRNA binding
- Chromatin associated protein KTI12
- NK
- alcohol group acceptor phosphotransferase
- enzyme
- O-phosphoseryl-tRNASec kinase
- AAA domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PSTK gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- translation
Molecular Function
What the gene product does at the molecular level
- ATP binding
- L-seryl-tRNA(Sec) kinase activity
- tRNA binding
- kinase activity