Cfap44

Predicted to enable peptidase activity. Involved in sperm axoneme assembly. Acts upstream of or within several processes, including cilium organization; nucleus organization; and spermatogenesis. Predicted to be located in axoneme. Is expressed in choroid plexus and floor plate. Used to study spermatogenic failure 20. Human ortholog(s) of this gene implicated in spermatogenic failure 20. Orthologous to human CFAP44 (cilia and flagella associated protein 44). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cfap44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Cfap44 gene, providing context for its role in the cell.