Cfap44 Gene Summary [Rat]
Predicted to enable peptidase activity. Predicted to act upstream of or within cell morphogenesis; nucleus organization; and sperm axoneme assembly. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Human ortholog(s) of this gene implicated in spermatogenic failure 20. Orthologous to human CFAP44 (cilia and flagella associated protein 44). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cfap44 |
| Official Name | cilia and flagella associated protein 44 [Source:RGD Symbol;Acc:1559942] |
| Ensembl ID | ENSRNOG00000028077 |
| Bio databases IDs | |
| Aliases | cilia and flagella associated protein 44 |
| Synonyms | 6330444M21Rik, cilia and flagella associated protein 44, D16Ertd642e, Gm1750, LOC100364695, RGD1559942, SPGF20, WDR52 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cfap44 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RecF/RecN/SMC N terminal domain
- WD40 repeats
- peptidase
- WD domain, G-beta repeat
- WD40
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- axonemes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cfap44 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm axoneme assembly
- microtubule cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- motile cilium
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- peptidase activity