Crygb Gene Summary [Mouse]
A structural constituent of eye lens. Acts upstream of or within lens fiber cell morphogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system and eye. Used to study cataract 39 multiple types. Human ortholog(s) of this gene implicated in cataract 39 multiple types. Orthologous to human CRYGB (crystallin gamma B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Crygb |
| Official Name | crystallin, gamma B [Source:MGI Symbol;Acc:MGI:88522] |
| Ensembl ID | ENSMUSG00000073658 |
| Bio databases IDs | |
| Aliases | crystallin, gamma B |
| Synonyms | CRYG2, Cryg-3, crystallin gamma B, crystallin, gamma B, crystallin γ B, crystallin, γ B, CTRCT39, DGcry-3, Nop, γ B crystallin |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Crygb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of eye lens
- protein binding
- Beta/Gamma crystallin
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Crygb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- lens fiber cell morphogenesis
- lens development in camera-type eye
- visual perception
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- structural constituent of eye lens