Golga5 Gene Summary [Mouse]
Predicted to enable protein homodimerization activity; protein-macromolecule adaptor activity; and small GTPase binding activity. Predicted to be involved in Golgi organization and retrograde transport, vesicle recycling within Golgi. Located in Golgi membrane. Is expressed in several structures, including alimentary system; central nervous system; limb bud; liver; and spleen. Orthologous to human GOLGA5 (golgin A5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Golga5 |
| Official Name | golgi autoantigen, golgin subfamily a, 5 [Source:MGI Symbol;Acc:MGI:1351475] |
| Ensembl ID | ENSMUSG00000021192 |
| Bio databases IDs | |
| Aliases | golgi autoantigen, golgin subfamily a, 5 |
| Synonyms | golgin A5, GOLIM5, Ret-II, RFG5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Golga5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Crescentin protein
- Autophagy protein 16 (ATG16)
- protein binding activity, bridging
- enzyme binding
- coiled-coil domain
- protein binding
- Calcium binding and coiled-coil domain (CALCOCO1) like
- Golgin subfamily A member 5
- kinase
- Domain of unknown function (DUF4686)
- transmembrane domain
- Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
- protein homodimerization
- Intermediate filament protein
- Outer membrane protein (OmpH-like)
- Septation ring formation regulator, EzrA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi-enriched fraction
- cellular membrane
- Golgi Apparatus
- Golgi membrane
- cis Golgi networks
- transport vesicles
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Golga5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- Golgi organization
- retrograde transport, vesicle recycling within Golgi
- Golgi vesicle transport
Cellular Component
Where in the cell the gene product is active
- cis-Golgi network
- membrane
- Golgi apparatus
- Golgi membrane
- transport vesicle
- Golgi cisterna
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity
- small GTPase binding