Amy1 Gene Summary [Mouse]

Enables amylase activity. Acts upstream of or within response to bacterium. Located in extracellular space. Is expressed in several structures, including nervous system; pancreas; and submandibular gland. Orthologous to several human genes including AMY2B (amylase alpha 2B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Amy1
Official Name
amylase 1, salivary [Source:MGI Symbol;Acc:MGI:88019]
Ensembl ID
ENSMUSG00000074264
Bio databases IDs NCBI: 11722 Ensembl: ENSMUSG00000074264
Aliases amylase 1, salivary
Synonyms Alpha Amylase, Am, Amy1a, amylase 1, salivary, Amylase 1 α, amylase alpha 1, amylase α 1, C030014B17RIK, α Amylase
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Amy1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • binding protein
  • Alpha amylase catalytic domain family
  • amylase
  • calcium ion binding
  • Alpha amylase, catalytic domain
  • enzyme
  • Alpha amylase, C-terminal all-beta domain
  • alpha-amylase
  • Maltogenic Amylase, C-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • doxorubicin induced cardiotoxicity
regulated by
  • AGT
  • heavy metal
  • progesterone
  • PSEN1
  • (R,R)-1,12-dimethylspermine
  • SAT1
  • CCK
  • maslinic acid
  • IQM 95333
  • FGF19

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Endoplasmic Reticulum
  • ER-to-Golgi intermediate compartment
  • endoplasmic reticulum buds

Gene-Specific Assays for Results You Can Trust

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