Sned1 Gene Summary [Mouse]
Predicted to enable Notch binding activity. Predicted to be involved in cell-matrix adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; limb interdigital region; and mesothelium. Orthologous to human SNED1 (sushi, nidogen and EGF like domains 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sned1 |
| Official Name | sushi, nidogen and EGF-like domains 1 [Source:MGI Symbol;Acc:MGI:3045960] |
| Ensembl ID | ENSMUSG00000047793 |
| Bio databases IDs | |
| Aliases | sushi, nidogen and EGF-like domains 1 |
| Synonyms | 6720455I24Rik, AI642697, D430044C15RIK, DKFZp586B2420, FLJ00133, IRE-BP1, Snep, SST3, sushi, nidogen and EGF-like domains 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sned1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CCP
- Nidogen-like
- FN3
- Human growth factor-like EGF
- Sushi repeat (SCR repeat)
- Fibronectin type 3 domain
- SUSHI repeat
- EGF_CA
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- perinuclear region
- Nucleus
- extracellular matrix
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sned1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell-matrix adhesion
Cellular Component
Where in the cell the gene product is active
- extracellular matrix
- extracellular region
Molecular Function
What the gene product does at the molecular level
- calcium ion binding
- Notch binding