Wt1os Gene Summary [Mouse]
Orthologous to human WT1-AS (WT1 antisense RNA). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Long Non-Coding RNA |
| Official Symbol | Wt1os |
| Official Name | Wilms tumor 1 homolog, opposite strand [Source:MGI Symbol;Acc:MGI:2138884] |
| Ensembl ID | ENSMUSG00000074987 |
| Bio databases IDs | |
| Aliases | Wilms tumor 1 homolog, opposite strand |
| Synonyms | 6030498F17, WIT-1, WT1 antisense, WT1 antisense RNA, WT1-AS1, Wt1os, WT1 transcription factor, opposite strand |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wt1os often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- inguinal hernia
- metabolic syndrome X
- organismal death
- hypertension
- cardiovascular disorder
- pelvic organ prolapse
- non-insulin-dependent diabetes mellitus
- cervical squamous cell carcinoma
- squamous cell cervical cancer
- endometrial carcinoma
regulated by
- PLAG1
- decitabine
regulates
- TP53
role in cell
- proliferation
- apoptosis
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wt1os gene, providing context for its role in the cell.
Molecular Function
What the gene product does at the molecular level
- protein binding