Pdf Gene Summary [Mouse]

Predicted to enable peptide deformylase activity. Predicted to be involved in positive regulation of cell population proliferation and protein modification process. Predicted to be active in mitochondrion. Orthologous to human PDF (peptide deformylase, mitochondrial). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Nonsense Mediated Decay
Official Symbol
Pdf
Official Name
peptide deformylase (mitochondrial) [Source:MGI Symbol;Acc:MGI:1915273]
Ensembl ID
ENSMUSG00000078931
Bio databases IDs NCBI: 68023 Ensembl: ENSMUSG00000078931
Aliases peptide deformylase (mitochondrial)
Synonyms 2610019N19Rik, LOC100363967, LOC686957, peptide deformylase (mitochondrial), peptide deformylase, mitochondrial
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pdf often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Pep_deformylase
  • peptide deformylase
  • enzyme

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
role in cell
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pdf gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • positive regulation of cell proliferation
  • N-terminal protein amino acid modification
  • co-translational protein modification
  • peptidyl-methionine modification
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • peptide deformylase activity

Gene-Specific Assays for Results You Can Trust

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