Itih5l-ps Gene Summary [Mouse]

The protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain. The light chain confers the protease-inhibitor function, while the heavy chains are involved in mediating protein-protein interactions with the components of the extracellular matrix. [provided by RefSeq, Sep 2009]

Details

Type
Transcribed Unprocessed Pseudogene
Official Symbol
Itih5l-ps
Official Name
inter-alpha (globulin) inhibitor H5-like, pseudogene [Source:MGI Symbol;Acc:MGI:2685232]
Ensembl ID
ENSMUSG00000087149
Bio databases IDs NCBI: 634882 Ensembl: ENSMUSG00000087149
Aliases inter-alpha (globulin) inhibitor H5-like, pseudogene
Synonyms dJ14O9.1, Gm386, inter-alpha-trypsin inhibitor heavy chain family member 6, inter-α-trypsin inhibitor heavy chain family member 6, ITIH5L, Itih5l-ps, Itih6-ps1, UNQ6369
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Itih5l-Ps often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Inter-alpha-trypsin inhibitor heavy chain C-terminus
  • marine proteobacterial sortase target protein
  • Vault protein inter-alpha-trypsin domain
  • von Willebrand factor (vWF) type A domain
  • vWFA
  • von Willebrand factor type A domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • egg allergy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Itih5l-Ps gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • hyaluronan metabolic process

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase inhibitor activity
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.