Ppp2r3d Gene Summary [Mouse]
Enables calcium-dependent protein serine/threonine phosphatase activity; chromatin binding activity; and protein phosphatase regulator activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of cell population proliferation; and protein dephosphorylation. Part of protein phosphatase type 2A complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human PPP2R3B (protein phosphatase 2 regulatory subunit B''beta). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp2r3d |
| Official Name | protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta [Source:MGI Symbol;Acc:MGI:1335093] |
| Ensembl ID | ENSMUSG00000093803 |
| Bio databases IDs | |
| Aliases | protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta |
| Synonyms | CAAA01125382.1, LOC108167320, LOC108167694, PP2A B''-PR59, PP2A PR59, Ppp2r3, Ppp2r3a, Ppp2r3b, PR59, protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta, protein phosphatase 2 (formerly 2A), regulatory subunit B'', δ, protein phosphatase 2, regulatory subunit B'', beta, protein phosphatase 2, regulatory subunit B'', β |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp2r3d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- serine/threonine protein phosphatase 2A regulatory subunit B''
- EF-hand domain
- calcium-dependent protein serine/threonine phosphatase
- EF-hand domain pair
- EF hand
- phosphatase
- protein phosphatase regulator
- chromatin binding
- protein binding
Pathways
Biological processes and signaling networks where the Ppp2r3d gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cilia
- cytosol
- nucleoplasm