Rcc1l Gene Summary [Rat]
Predicted to enable guanyl-nucleotide exchange factor activity and rRNA binding activity. Predicted to be involved in mitochondrial fusion; mitochondrial ribosome assembly; and positive regulation of mitochondrial translation. Predicted to be located in mitochondrial matrix and mitochondrial membrane. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome. Orthologous to human RCC1L (RCC1 like). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rcc1l |
| Official Name | RCC1 like [Source:RGD Symbol;Acc:1307558] |
| Ensembl ID | ENSRNOG00000001483 |
| Bio databases IDs | |
| Aliases | RCC1 like |
| Synonyms | 5730496C04Rik, LOC653375, RCC1 like, reculator of chromosome condensation 1 like, WBSCR16 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rcc1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Regulator of chromosome condensation (RCC1) repeat
- rRNA binding
- guanyl-nucleotide exchange factor
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial membrane
- mitochondrial matrix
- mitochondrial inner membrane
- paraspeckle-like structures
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rcc1l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of mitochondrial translation
- mitochondrial fusion
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- RNA binding
- guanyl-nucleotide exchange factor activity
- rRNA binding