Dzip3 Gene Summary [Rat]
Predicted to enable several functions, including phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in cytoplasm. Orthologous to human DZIP3 (DAZ interacting zinc finger protein 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dzip3 |
| Official Name | DAZ interacting zinc finger protein 3 [Source:RGD Symbol;Acc:1563278] |
| Ensembl ID | ENSRNOG00000001956 |
| Bio databases IDs | |
| Aliases | DAZ interacting zinc finger protein 3 |
| Synonyms | 2310047C04RIK, 2A-HUB, 6430549P11Rik, A230104G20, DAZ interacting protein 3, zinc finger, DAZ interacting zinc finger protein 3, hRUL138, KIAA0675, PPP1R66, RGD1563278, UURF2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dzip3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- coiled-coil domain
- enzyme
- E3 ubiquitin-protein ligase TTC3/DZIP3 domain
- Ring finger domain
- protein binding
- RING-like zinc finger
- RNA binding
- DZIP3/ hRUL138-like HEPN
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- ubiquitin-protein transferase activity
- tail domain
- phosphatase binding
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dzip3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein polyubiquitination
Cellular Component
Where in the cell the gene product is active
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- phosphatase binding
- ubiquitin-protein ligase activity
- protein binding
- RNA binding
- metal ion binding
- polyubiquitin binding