Cd47 Gene Summary [Rat]

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in several processes, including cellular response to cytokine stimulus; positive regulation of monocyte extravasation; and regulation of phagocytosis. Located in cell surface. Orthologous to human CD47 (CD47 molecule). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cd47
Official Name
Cd47 molecule [Source:RGD Symbol;Acc:2308]
Ensembl ID
ENSRNOG00000001964
Bio databases IDs NCBI: 29364 Ensembl: ENSRNOG00000001964
Aliases Cd47 molecule
Synonyms Cd47 molecule, Itgp
Species
Rat, Rattus norvegicus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cd47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • extracellular domain
  • signaling receptor activity
  • binding protein
  • immunoglobulin domain
  • cell adhesion molecule binding
  • CD47 transmembrane region

Pathways

Biological processes and signaling networks where the Cd47 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • MYC
  • N-methyl-D-aspartate
  • amphetamine
  • benzene
  • trichloroethylene
  • methylmercury
  • poly rI:rC-RNA
regulates
role in cell
  • fusion
  • binding
  • reorganization
  • response by
  • phagocytosis by
  • assembly
  • extravasation
  • transmigration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • glutaminergic synapse
  • presynaptic regions
  • cell surface
  • growth cone
  • exosomes

Gene-Specific Assays for Results You Can Trust

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