Prpsap2 Gene Summary [Rat]
Predicted to enable enzyme regulator activity and identical protein binding activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to act upstream of or within bone development. Part of ribose phosphate diphosphokinase complex. Orthologous to human PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Prpsap2 |
| Official Name | phosphoribosyl pyrophosphate synthetase-associated protein 2 [Source:RGD Symbol;Acc:620207] |
| Ensembl ID | ENSRNOG00000002724 |
| Bio databases IDs | |
| Aliases | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| Synonyms | A230054F23Rik, PAP41, phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Prpsap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme inhibitor activity
- Phosphoribosyl transferase (PRT)-type I domain
- ribose-phosphate pyrophosphokinase
- protein binding
- Phosphoribosyl synthetase-associated domain
- PRK00934
- N-terminal domain of ribose phosphate pyrophosphokinase
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Prpsap2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- purine nucleotide biosynthetic process
- nucleobase-containing compound metabolic process
- 5-phosphoribose 1-diphosphate biosynthetic process
- bone development
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- ribose phosphate diphosphokinase complex
Molecular Function
What the gene product does at the molecular level
- magnesium ion binding
- ATP binding
- identical protein binding
- protein binding
- enzyme inhibitor activity
- ribose phosphate diphosphokinase activity