Afm Gene Summary [Rat]

Predicted to enable vitamin E binding activity. Predicted to be involved in protein stabilization; protein transport within extracellular region; and vitamin transport. Located in extracellular space. Orthologous to human AFM (afamin). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Afm
Official Name
afamin [Source:RGD Symbol;Acc:628614]
Ensembl ID
ENSRNOG00000002878
Bio databases IDs NCBI: 282708 Ensembl: ENSRNOG00000002878
Aliases afamin
Synonyms afamin, Serum albumin
Species
Rat, Rattus norvegicus

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Afm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ALBUMIN
  • tocopherol binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • diflunisal glucuronide
  • APP
  • zomepirac glucuronide
  • clofibric acid glucuronide
  • valproic acid glucuronide
regulated by
  • IgG
  • dexamethasone
  • Afm
  • dextran
  • zomepirac
  • clofibric acid
  • IC542
  • diflunisal
regulates

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • vesicles
  • Endoplasmic Reticulum
  • plasma

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.