Camta2 Gene Summary [Rat]
Predicted to enable several functions, including DNA binding activity; histone deacetylase binding activity; and transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cardiac muscle hypertrophy in response to stress and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus. Orthologous to human CAMTA2 (calmodulin binding transcription activator 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Camta2 |
| Official Name | calmodulin binding transcription activator 2 [Source:RGD Symbol;Acc:1311296] |
| Ensembl ID | ENSRNOG00000004283 |
| Bio databases IDs | |
| Aliases | calmodulin binding transcription activator 2 |
| Synonyms | calmodulin binding transcription activator 2, Kiaa0909-hp, mKIAA0909 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Camta2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- Ankyrin repeats (many copies)
- CG-1 domain
- transcription co-activator
- IPT/TIG domain
- Ankyrin repeats (3 copies)
- transcription factor binding
- histone deacetylase binding
- chromatin binding
- protein binding
- sequence-specific DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Camta2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription from RNA polymerase II promoter
- cardiac muscle hypertrophy in response to stress
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- chromatin
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription cofactor activity
- transcription coactivator activity
- histone deacetylase binding
- double-stranded DNA binding
- sequence-specific DNA binding
- chromatin binding