Arf2 Gene Summary [Rat]

Predicted to enable GTP binding activity. Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Predicted to be located in Golgi apparatus. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human ARL17B (ARF like GTPase 17B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Arf2
Official Name
ADP-ribosylation factor 2 [Source:RGD Symbol;Acc:621271]
Ensembl ID
ENSRNOG00000004807
Bio databases IDs NCBI: 79119 Ensembl: ENSRNOG00000004807
Aliases ADP-ribosylation factor 2
Synonyms ADP ribosylation factor, ADP-ribosylation factor 2, ARF GTPase 2
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Arf2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sar1p-like members of the Ras-family of small GTPases
  • GTP binding
  • ADP-ribosylation factor family
  • Ras of Complex, Roc, domain of DAPkinase
  • ADP-ribosylation factor
  • P-loop containing Nucleoside Triphosphate Hydrolases

Pathways

Biological processes and signaling networks where the Arf2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • lipopolysaccharide
  • MYC
  • bee venom
  • GNAQ
  • Lethal toxin
  • MAPT
  • EIF2AK3
  • cyclosporin A
  • tunicamycin

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Golgi Apparatus

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.