Zscan20 Gene Summary [Rat]

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZSCAN20 (zinc finger and SCAN domain containing 20). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Zscan20
Official Name
zinc finger and SCAN domain containing 20 [Source:RGD Symbol;Acc:1562996]
Ensembl ID
ENSRNOG00000005886
Bio databases IDs NCBI: 500549 Ensembl: ENSRNOG00000005886
Aliases zinc finger and SCAN domain containing 20
Synonyms C130001F22, KOX29, RGD1562996, ZFP-31, zinc finger and SCAN domain containing 20, zinc finger and SCAN domains 20, Zkscan20, ZNF31, ZNF360
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zscan20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc finger, C2H2 type
  • Myb/SANT-like DNA-binding domain
  • leucine rich region
  • zinc finger
  • transcription regulator
  • Zinc-finger double domain
  • GT1, myb-like, SANT family
  • SCAN domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • hepatocellular carcinoma
  • liver cancer
  • epithelial cancer
  • organismal death
  • neuropathic pain
  • Brugada syndrome
regulates
role in cell
  • expression in
  • proliferation
  • migration
  • invasion by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Zscan20 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • metal ion binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • sequence-specific DNA binding RNA polymerase II transcription factor activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.