Lrtm2 Gene Summary [Rat]
Predicted to be involved in axonogenesis. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in membrane. Orthologous to human LRTM2 (leucine rich repeats and transmembrane domains 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrtm2 |
| Official Name | leucine-rich repeats and transmembrane domains 2 [Source:RGD Symbol;Acc:1587001] |
| Ensembl ID | ENSRNOG00000007508 |
| Bio databases IDs | |
| Aliases | leucine-rich repeats and transmembrane domains 2 |
| Synonyms | A230084J22, leucine-rich repeats and transmembrane domains 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lrtm2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Leucine-rich repeats, outliers
- Leucine-rich repeats, typical (most populated) subfamily
- Leucine rich repeat
- Leucine rich repeat C-terminal domain
- Leucine rich repeat N-terminal domain
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Lrtm2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative chemotaxis
- axon guidance
- positive regulation of synapse assembly
Cellular Component
Where in the cell the gene product is active
- membrane
Molecular Function
What the gene product does at the molecular level
- Roundabout binding
- heparin binding