Gprc5d Gene Summary [Rat]

Predicted to enable protein kinase activator activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of receptor complex. Predicted to be active in extracellular exosome; intracellular membrane-bounded organelle; and plasma membrane. Orthologous to human GPRC5D (G protein-coupled receptor class C group 5 member D). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gprc5d
Official Name
G protein-coupled receptor, class C, group 5, member D [Source:RGD Symbol;Acc:1563887]
Ensembl ID
ENSRNOG00000008439
Bio databases IDs NCBI: 500349 Ensembl: ENSRNOG00000008439
Aliases G protein-coupled receptor, class C, group 5, member D
Synonyms G protein-coupled receptor class C group 5 member D, G protein-coupled receptor, class C, group 5, member D, G protein-coupled receptor, family C, group 5, member D, RGD1563887
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gprc5d often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • G-protein coupled receptor
  • protein binding
  • 7 transmembrane sweet-taste receptor of 3 GCPR
  • seven-transmembrane G protein-coupled receptor superfamily

Pathways

Biological processes and signaling networks where the Gprc5d gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • relapsed multiple myeloma
  • plasma cell myeloma
  • refractory multiple myeloma
  • refractory relapsed multiple myeloma
regulated by
  • laquinimod
role in cell
  • growth
  • cisplatin sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gprc5d gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • G-protein coupled receptor signaling pathway

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • intracellular membrane-bounded organelle
  • receptor complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • G-protein coupled receptor activity
  • protein binding
  • protein kinase activator activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.